When your team is dropped into the Complex, you enter the Rundown. It’s a sequence of expeditions where you fill the work order issued by the Warden, the unknown entity holding you captive. Survive all the expeditions to complete your mission and clear the Rundown. Of course, the further down you go into this abandoned research facility, the tougher things get. But that won't stop you because while don't know what the Warden is up to, your program doesn’t allow for questions.
The Warden has issued a new work order
A new work order from the Warden means a new Rundown. When a Rundown is released, the existing one is deleted forever - there’s no going back. New Rundowns will drop periodically over the lifetime of the game, bringing your team grisly new ways to suffer.